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Top 23 Python Web Projects
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system-design-primer
Learn how to design large-scale systems. Prep for the system design interview. Includes Anki flashcards.
Project mention: 2026: The average developer's year disappears and the most will struggle | dev.to | 2025-11-27One of the best free resources for real engineering fundamentals. https://github.com/donnemartin/system-design-primer
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InfluxDB
InfluxDB – Built for High-Performance Time Series Workloads. InfluxDB 3 OSS is now GA. Transform, enrich, and act on time series data directly in the database. Automate critical tasks and eliminate the need to move data externally. Download now.
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Link (Github): https://github.com/AUTOMATIC1111/stable-diffusion-webui
- Project mention: Observability Practices: Implementing Real-World Monitoring With Python and Prometheus | dev.to | 2025-12-03
FastAPI – https://fastapi.tiangolo.com
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After some hard work (the process is detailed here), I successfully submitted my first PR. I learned a tremendous amount during the review process. I hope to use this feedback to significantly improve my code quality and structure in future PRs.
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httpie
🥧 HTTPie CLI — modern, user-friendly command-line HTTP client for the API era. JSON support, colors, sessions, downloads, plugins & more. (by httpie)
If you prefer HTTPie:
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glance
Glances an Eye on your system. A top/htop alternative for GNU/Linux, BSD, Mac OS and Windows operating systems.
Glances is nice. I think it is a clone of HP-UX Glance.
https://nicolargo.github.io/glances/
- Project mention: Prediction: AI will make formal verification go mainstream | news.ycombinator.com | 2025-12-16
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Stream
Stream - Scalable APIs for Chat, Feeds, Moderation, & Video. Stream helps developers build engaging apps that scale to millions with performant and flexible Chat, Feeds, Moderation, and Video APIs and SDKs powered by a global edge network and enterprise-grade infrastructure.
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flet
Flet enables developers to easily build realtime web, mobile and desktop apps in Python. No frontend experience required.
Project mention: FletX: Bring Reactive Power to Your Python UI with GetX-Like Simplicity | dev.to | 2025-06-15Meet FletX — a lightweight framework built on top of Flet that brings reactivity and clean architecture to Python GUI apps.
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falcon
The no-magic web API and microservices framework for Python developers, with a focus on reliability and performance at scale.
- Project mention: Robyn: A curiously fast Python/Rust web framework | news.ycombinator.com | 2025-11-24
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Flask-AppBuilder
Simple and rapid application development framework, built on top of Flask. includes detailed security, auto CRUD generation for your models, google charts and much more. Demo (login with guest/welcome) - http://flaskappbuilder.pythonanywhere.com/
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connexion
Connexion is a modern Python web framework that makes spec-first and api-first development easy.
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LitServe
Build custom inference engines for models, agents, multi-modal systems, RAG, pipelines and more.
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- Project mention: Show HN: Rio – Modern Web Apps in Pure Python, No JavaScript/HTML/CSS Needed | news.ycombinator.com | 2025-03-08
Hey HN,
Over the past 10 months, my friends and I created an open source project called Rio to help Python developers build modern web apps without needing HTML, CSS, or JavaScript. Whether you're working on a simple internal tool or a complex multi-page app, Rio lets you stay in the Python ecosystem without needing to learn frontend frameworks.
With Rio, the UI is defined using Python components, inspired by React and Flutter. Instead of writing HTML/CSS, you compose reusable UI elements in Python and let Rio handle rendering and state updates. The backend and frontend stay seamlessly connected using WebSockets, so data syncs automatically without manual API calls. Since Rio is fully Python-native, you can integrate it with any Python library, from data science tools to AI models.
Many Python projects rely on popular libraries like React internally, but the core benefits and elegance of these libraries are often diluted in the process. Unlike wrapper frameworks, Rio is built from scratch, offering a cleaner, faster, and more efficient development experience specifically for Python.
We’ve seen users build everything from CRM tools to dashboards, LLM interfaces, and interactive reports using Rio. If you’re a Python developer who has wanted a better way to build web apps without learning JavaScript, we’d love to hear your thoughts!
[Github] https://github.com/rio-labs/rio
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SaaSHub
SaaSHub - Software Alternatives and Reviews. SaaSHub helps you find the best software and product alternatives
NOTE: The open source projects on this list are ordered by number of github stars. The number of mentions indicates repo mentiontions in the last 12 Months or since we started tracking (Dec 2020).
Python Web discussion
Python Web related posts
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Reflections on the Djangonaut Space Journey 🦄
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2026: The average developer's year disappears and the most will struggle
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Show HN: PhantomCollect – Open-Source Web Data Collection Framework in Python
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AI scrapers request commented scripts
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Flask vs. Django: Which Framework Should You Choose For Your Project?
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Django 6.0 alpha 1 released
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Set up your own personal AI Frankenstack: DIY edition
- A note from our sponsor - InfluxDB www.influxdata.com | 22 Dec 2025
Index
What are some of the best open-source Web projects in Python? This list will help you:
| # | Project | Stars |
|---|---|---|
| 1 | system-design-primer | 329,920 |
| 2 | stable-diffusion-webui | 159,018 |
| 3 | fastapi | 93,326 |
| 4 | Django | 86,197 |
| 5 | httpie | 37,170 |
| 6 | glance | 30,984 |
| 7 | reflex | 27,821 |
| 8 | sanic | 18,600 |
| 9 | flet | 15,019 |
| 10 | qutebrowser | 11,134 |
| 11 | django-cms | 10,607 |
| 12 | falcon | 9,770 |
| 13 | Robyn | 6,801 |
| 14 | oppia | 6,349 |
| 15 | Flask-AppBuilder | 4,934 |
| 16 | MechanicalSoup | 4,831 |
| 17 | connexion | 4,577 |
| 18 | Kinto | 4,395 |
| 19 | LitServe | 3,737 |
| 20 | toapi | 3,535 |
| 21 | Flexx | 3,340 |
| 22 | rio | 3,324 |
| 23 | awesome-discord-communities | 3,243 |
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InfluxDB 3 OSS is now GA. Transform, enrich, and act on time series data directly in the database. Automate critical tasks and eliminate the need to move data externally. Download now.
www.influxdata.com