David F. Carr's presentation at WordCamp Miami 2011 discusses customizing WordPress through plugins and themes, explaining the advantages of using WordPress for web development, including its strong community, SEO friendliness, and rich resources. He covers the anatomy of themes, the WordPress file hierarchy, and how to leverage hooks and filters to alter site behavior and content management. The presentation also highlights the importance of security and database management in WordPress development, along with practical coding examples and resources for further learning.