The ISA bus is quite old in design and is a notoriously poor performer, but it still holds a good part of the market for extension devices. If speed is not important and you want to support old motherboards, an ISA implementation is preferable to PCI. An additional advantage of this old standard is that if you are an electronic hobbyist, you can easily build your own ISA devices, something definitely not possible with PCI.

On the other hand, a great disadvantage of ISA is that it’s tightly bound to the PC architecture; the interface bus has all the limitations of the 80286 processor and causes endless pain to system programmers. The other great problem with the ISA design (inherited from the original IBM PC) is the lack of geographical addressing, which has led to many problems and lengthy unplug-rejumper-plug-test cycles to add new devices. It’s interesting to note that even the oldest Apple II computers were already exploiting geographical addressing, and they featured jumperless expansion boards.

Despite its great disadvantages, ISA is still used in several unexpected places. For example, the VR41xx series of MIPS processors used in several palmtops features an ISA-compatible expansion bus, strange as it seems. The reason behind these unexpected uses of ISA is the extreme low cost of some legacy hardware, like 8390-based Ethernet cards, so a CPU with ISA electrical signaling can easily exploit the awful but cheap PC devices.