The Best Python Web App Frameworks in 2025

This page summarizes the projects mentioned and recommended in the original post on dev.to

Stream - Scalable APIs for Chat, Feeds, Moderation, & Video.
Stream helps developers build engaging apps that scale to millions with performant and flexible Chat, Feeds, Moderation, and Video APIs and SDKs powered by a global edge network and enterprise-grade infrastructure.
getstream.io
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InfluxDB – Built for High-Performance Time Series Workloads
InfluxDB 3 OSS is now GA. Transform, enrich, and act on time series data directly in the database. Automate critical tasks and eliminate the need to move data externally. Download now.
www.influxdata.com
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  1. streamlit

    Streamlit β€” A faster way to build and share data apps.

    Streamlit

  2. Stream

    Stream - Scalable APIs for Chat, Feeds, Moderation, & Video. Stream helps developers build engaging apps that scale to millions with performant and flexible Chat, Feeds, Moderation, and Video APIs and SDKs powered by a global edge network and enterprise-grade infrastructure.

    Stream logo
  3. py-shiny

    Shiny for Python

    Streamlit is one such tool that offers a simple, Pythonic approach. However, it suffers from two main weaknesses: the script needs to be re-run after every user interaction, and customizing the look and feel of a Streamlit app is dificult. Shiny for Python is a great alternative for building dashboards and small data-backed apps. Shiny only re-renders code as necessary - not the entire script, and offers more flexibility in styling your app. NiceGUI offers a similar approach, but with less intuitive code and no tutorials or live examples, is more of a challenge to get started with. Reflex is a great option if you want more flexibility in building your app's UI, but you'll need to learn a bit of traditional web development.

  4. reflex

    πŸ•ΈοΈ Web apps in pure Python 🐍

    Streamlit is one such tool that offers a simple, Pythonic approach. However, it suffers from two main weaknesses: the script needs to be re-run after every user interaction, and customizing the look and feel of a Streamlit app is dificult. Shiny for Python is a great alternative for building dashboards and small data-backed apps. Shiny only re-renders code as necessary - not the entire script, and offers more flexibility in styling your app. NiceGUI offers a similar approach, but with less intuitive code and no tutorials or live examples, is more of a challenge to get started with. Reflex is a great option if you want more flexibility in building your app's UI, but you'll need to learn a bit of traditional web development.

  5. nicegui

    Create web-based user interfaces with Python. The nice way.

    Streamlit is one such tool that offers a simple, Pythonic approach. However, it suffers from two main weaknesses: the script needs to be re-run after every user interaction, and customizing the look and feel of a Streamlit app is dificult. Shiny for Python is a great alternative for building dashboards and small data-backed apps. Shiny only re-renders code as necessary - not the entire script, and offers more flexibility in styling your app. NiceGUI offers a similar approach, but with less intuitive code and no tutorials or live examples, is more of a challenge to get started with. Reflex is a great option if you want more flexibility in building your app's UI, but you'll need to learn a bit of traditional web development.

NOTE: The number of mentions on this list indicates mentions on common posts plus user suggested alternatives. Hence, a higher number means a more popular project.

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Did you know that Python is
the 2nd most popular programming language
based on number of references?