The Diophantine equation $x^2 - 34y^2 = -1$ has no integer solutions, even though it has solutions in ${\bf Z}_p$ for all $p$ (including $p = \infty$ if we understand "${\bf Z}_\infty$" as $\bf R$). This is the first example of the failure of the Hasse principle for the minus case of the Fermat-Pell equation $x^2 - \Delta y^2 = \pm 1$ (with $\Delta $ a fixed positive integer that is not a square), or equivalently for the existence of units of norm $-1$ in ${\bf Z}[\sqrt{\Delta}]$. It can also be regarded as the first example of a nontrivial element of the "Tate-Šafarevič group" for the torus $x^2 - \Delta y^2 = +1$ (since $x^2 - \Delta y^2 = -1$ is a principal homogeneous space for that torus).
 [NB the equation $x^2 - 34y^2 = -1$ does have rational solutions, such as $(x,y) = (5/3,1/3)$. Indeed Minkowski already showed that a quadratic equation in any number of variables has a rational solution iff it has a solution in each ${\bf Q}_p$ and in ${\bf R}$; Hasse generalized this from ${\bf Q}$ to an arbitrary number field.]
 [Added later:] In general $x^2 - \Delta y^2 = -1$ has solutions in every ${\bf Z}_p$ iff $\Delta$ is either a product of primes congruent to $1 \bmod 4$ or twice such a product; equivalently, iff $\Delta$ is the sum of two coprime squares. If such $\Delta$ is of the form $n^2 \pm 2$ then $(n + \sqrt\Delta)^2 / 2$ is a unit of norm $+1$, and is fundamental unless $\Delta=2$. This accounts for infinitely many examples, including the first two, $\Delta = 34 = 5^2 + 3^2 = 6^2 - 2$ and $\Delta = 146 = 11^2 + 5^2 = 12^2 + 2$ (see  OEIS sequence A031398). The infinitude may be shown with a polynomial identity such as $$ (2t^2+2t+1)^2 + (2t+1)^2 = (2t^2+2t+2)^2 - 2 $$ which recovers $\Delta = 34$ for $t=1$. It's then a natural question to ask: as $M \rightarrow \infty$, among those positive $\Delta < M$ that are sums of two coprime squares, for what fraction does $x^2 - \Delta y^2 = -1$ have solutions? I guess that it is conjectured, but not known, that there is a positive limit strictly smaller than $1$.