This article summarizes five common performance problems in .NET applications: 1. Synchronization and locking issues that can serialize thread execution. The solution is to limit synchronized blocks to only necessary code. 2. Excessive or unnecessary logging, such as logging exceptions at multiple levels or leaving debug logging enabled in production. 3. Dependencies on external libraries that are not optimized, tested, or used correctly can negatively impact performance. 4. Underlying database issues like inefficient queries can slow applications. Database architects should review data models and queries. 5. Underlying infrastructure problems in hardware, operating systems, networks or load balancers that are not tuned can impact performance.