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Copy file name to clipboardExpand all lines: arFramework3/Examples/ODE2UMAP/README.md
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The method is applied to a published model of the NFκB signalling pathway from [Almaden et al.](https://doi.org/10.1016/j.celrep.2014.11.024) for illustration.
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**Addional Software needed:**
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For the creation of the UMAPs you need the [Matlab implementation of the UMAP Algorithm](https://www.mathworks.com/matlabcentral/fileexchange/71902).
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**Cite:**
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*[A New Approximation Approach for Transient Differential Equation Models](https://www.frontiersin.org/journals/physics/articles/10.3389/fphy.2020.00070) - Kreutz C. *Front. Phys.*, 8, 70, 2020.
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*[Dynamic modelling of signalling pathways when ordinary differential equations are not feasible](https://academic.oup.com/bioinformatics/article/40/12/btae683/7903280) - Rachel T., et al. *Bioinformatics*, 40, 12, 2024.
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*[The Dose-Dependent Retarded Transient Function: A Novel Approach for Modelling Cellular Signalling Dynamics](https://freidok.uni-freiburg.de/) - Rachel T., Master’s Thesis, 2024.
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*[The Dose-Dependent Retarded Transient Function: A Novel Approach for Modelling Cellular Signalling Dynamics](https://doi.org/10.6094/UNIFR/263264) - Rachel T., Master’s Thesis, 2024.
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*[A Pathway Switch Directs BAFF Signaling to Distinct NFκB Transcription Factors in Maturing and Proliferating B Cells](https://doi.org/10.1016/j.celrep.2014.11.024) - Almaden J., Tsui R., Liu Y. et. al. *Cell Reports*, 9, 2014.
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*[UMAP : Uniform Manifold Approximation and Projection for Dimension Reduction](https://doi.org/10.48550/arXiv.1802.03426)- McInnes L., Healy J. and Melville J., 2020
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*[Uniform Manifold Approximation and Projection (UMAP)](https://www.mathworks.com/matlabcentral/fileexchange/71902) - Meehan C., Ebrahimian J., Moore W., and Meehan S., *MATLAB Central File Exchange*, 2022.
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