Three treatments were compared to test their relative efficacy (effectiveness) in treating Type 2 Diabetes in patients aged 10-17 who were being treated with metformin. The primary outcome was lack of glycemic control (or not); lacking glycemic control means the patient still needed insulin, which is not the preferred outcome for a patient.
Format
A data frame with 699 observations on the following 2 variables.
- treatment
The treatment the patient received.
- outcome
Whether there patient still needs insulin (
failure) or met a basic positive outcome bar (success).
Source
Zeitler P, et al. 2012. A Clinical Trial to Maintain Glycemic Control in Youth with Type 2 Diabetes. N Engl J Med.
Details
Each of the 699 patients in the experiment were randomized to one of the following treatments: (1) continued treatment with metformin (coded as met), (2) formin combined with rosiglitazone (coded as rosi), or or (3) a lifestyle-intervention program (coded as lifestyle).
Examples
lapply(diabetes2, table) #> $treatment #> #> lifestyle met rosi #> 234 232 233 #> #> $outcome #> #> failure success #> 319 380 #> (cont.table <- table(diabetes2)) #> outcome #> treatment failure success #> lifestyle 109 125 #> met 120 112 #> rosi 90 143 (m <- chisq.test(cont.table)) #> #> Pearson's Chi-squared test #> #> data: cont.table #> X-squared = 8.1645, df = 2, p-value = 0.01687 #> m$expected #> outcome #> treatment failure success #> lifestyle 106.7897 127.2103 #> met 105.8770 126.1230 #> rosi 106.3333 126.6667